| Active transposition in genomes. | |
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MedLine Citation:
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PMID: 23145912 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Transposons are DNA sequences capable of moving in genomes. Early evidence showed their accumulation in many species and suggested their continued activity in at least isolated organisms. In the past decade, with the development of various genomic technologies, it has become abundantly clear that ongoing activity is the rule rather than the exception. Active transposons of various classes are observed throughout plants and animals, including humans. They continue to create new insertions, have an enormous variety of structural and functional impact on genes and genomes, and play important roles in genome evolution. Transposon activities have been identified and measured by employing various strategies. Here, we summarize evidence of current transposon activity in various plant and animal genomes. |
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Authors:
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Cheng Ran Lisa Huang; Kathleen H Burns; Jef D Boeke |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Annual review of genetics Volume: 46 ISSN: 1545-2948 ISO Abbreviation: Annu. Rev. Genet. Publication Date: 2012 Dec |
Date Detail:
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Created Date: 2012-11-13 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0117605 Medline TA: Annu Rev Genet Country: United States |
Other Details:
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Languages: eng Pagination: 651-75 Citation Subset: IM |
Affiliation:
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Institute of Genetic Medicine and High Throughput Biology Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA; email: chuang36@jhmi.edu. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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