Document Detail


Active and passive smoking and risk of Parkinson's disease.
MedLine Citation:
PMID:  20175761     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
OBJECTIVE: To assess the association between active and passive smoking and the risk of Parkinson's disease (PD), a case-control study with 249 PD patients and 369 controls was carried out in Japan.
METHODS: Information on smoking was obtained through a self-administered questionnaire. Adjustment was made for age, sex, region of residence, educational level, and occupational exposure.
RESULTS: Ever having smoked cigarettes was associated with a reduced risk of PD [adjusted odds ratio = 0.38; 95% confidence interval (CI): 0.24-0.59]. Risk for former smokers was intermediate between the high risk for never smokers and the low risk for current smokers. Adjusted odds ratios for former and current smokers were 0.51 (95% CI: 0.32-0.82) and 0.12 (95% CI: 0.05-0.26), respectively. There was an inverse dose-response gradient with pack-years smoked. No significant association was detected for passive smoking exposure.
CONCLUSION: Our results appear to confirm data from previous epidemiological studies.
Authors:
K Tanaka; Yoshihiro Miyake; W Fukushima; S Sasaki; C Kiyohara; Y Tsuboi; T Yamada; T Oeda; T Miki; N Kawamura; N Sakae; H Fukuyama; Y Hirota; M Nagai;
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta neurologica Scandinavica     Volume:  122     ISSN:  1600-0404     ISO Abbreviation:  Acta Neurol. Scand.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-10-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370336     Medline TA:  Acta Neurol Scand     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  377-82     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 The Authors. Journal compilation © 2010 Blackwell Munksgaard.
Affiliation:
Department of Public Health, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
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MeSH Terms
Descriptor/Qualifier:
Investigator
Investigator/Affiliation:
Yasuhiko Baba / ; Tomonori Kobayashi / ; Hideyuki Sawada / ; Eiji Mizuta / ; Nagako Murase / ; Tsuyoshi Tsutada / ; Hiroyuki Shimada / ; Jun-ichi Kira / ; Tameko Kihira / ; Hidekazu Tomimoto / ; Takayuki Taniwaki / ; Hiroshi Sugiyama / ; Sonoyo Yoshida / ; Harutoshi Fujimura / ; Tomoko Saito / ; Kyoko Saida / ; Junko Fujitake / ; Naoki Fujii / ; Masatoshi Naito / ; Jun Arimizu / ; Takashi Nakagawa / ; Hirofumi Harada / ; Takayuki Sueta / ; Toshihiro Kikuta / ; George Umemoto / ; Eiichi Uchio / ; Hironori Migita / ; Kenichi Kazuki / ; Yoichi Ito / ; Hiroyoshi Iwaki / ; Kunihiko Siraki / ; Shinsuke Ataka / ; Hideo Yamane / ; Rie Tochino / ; Teruichi Harada / ; Yasushi Iwashita / ; Motoyuki Shimizu / ; Kenji Seki / ; Keiji Ando /

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