| Active expectant management in very early gestations complicated by premature rupture of the fetal membranes. | |
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MedLine Citation:
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PMID: 8169909 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Premature rupture of the membranes (PROM) in the previable gestation is frequently associated with fetal or neonatal death. Passive expectant management is successful in only a small minority of cases. Women presenting with PROM at < or = 27 weeks' gestation were treated with tocolysis and prophylactic antibiotics and delivered electively for lung maturity. The corrected perinatal survival was > 92%. The mean latency phase was 21.6 days (+/- 18.12 SD). Twenty-one percent of patients presented in labor; the mean latency phase for this subgroup was 14.4 (+/- 8.54) days. Nineteen patients (79%) had a latency phase > 7 days, and 14 (58%) had a latency phase > 14 days. Thirty-nine percent of infants required < 48 hours of mechanical ventilation. Six infants were delivered with intraventricular hemorrhage; in all cases it was grade 1 or 2. There were three (12.5%) postpartum infections and three septic neonates. Active expectant management using tocolysis and prophylactic antibiotics was associated with a prolonged latency phase, low infectious morbidity and good neonatal outcome. |
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Authors:
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S J Fortunato; S I Welt; M K Eggleston; E C Bryant |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of reproductive medicine Volume: 39 ISSN: 0024-7758 ISO Abbreviation: J Reprod Med Publication Date: 1994 Jan |
Date Detail:
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Created Date: 1994-06-01 Completed Date: 1994-06-01 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0173343 Medline TA: J Reprod Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 13-6 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, Wright State University, Dayton, Ohio. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Ceftizoxime / therapeutic use* Clinical Protocols Decision Trees Delivery, Obstetric / methods* Drug Therapy, Combination Female Fetal Membranes, Premature Rupture / complications*, diagnosis, therapy* Fetal Monitoring Fetal Organ Maturity Gestational Age Humans Infant, Newborn Infant, Premature* Magnesium Sulfate / therapeutic use* Pregnancy Pregnancy Outcome Pregnancy Trimester, Second Prospective Studies Terbutaline / therapeutic use* |
| Chemical | |
Reg. No./Substance:
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23031-25-6/Terbutaline; 68401-81-0/Ceftizoxime; 7487-88-9/Magnesium Sulfate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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