| Activation patterns during selective pacing of the left ventricle can be characterized using noninvasive electrocardiographic imaging. | |
| | |
MedLine Citation:
|
PMID: 17993307 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Noncontact endocardial mapping allows accurate beat-to-beat reconstruction of the reentrant pathway of ventricular tachycardia and improves outcomes after ablation. Several studies support electrocardiographic imaging (ECGI) as a means of noninvasively outlining epicardial activation despite constraints of internal geometry. However, few have explored its clinical application. This study aims to evaluate ECGI during selective left ventricular (LV) pacing, relative to an invasive approach. METHODS: Multisite pacing was performed within the left ventricles of 3 patients undergoing invasive procedures. Simultaneous recording of endocardial potentials using a noncontact multielectrode array and body surface potentials (BSP) using an 80-electrode torso vest was performed. A total of 16 recordings were made. The inverse solution was applied to BSP to reconstruct epicardial activation. Single-paced beats from real and virtual electrograms were used to construct 3-dimensional isochronal and isopotential maps. Endocardial and epicardial data were then superimposed onto a single geometry to allow quantitative comparison of activation foci. RESULTS: Good correlation was observed between endocardial activation patterns and those reconstructed from BSP using ECGI. This was repeatedly demonstrated in all LV regions except for the septum (3 recordings). Epicardial isochronal maps were able to locate early and late activation to mean distances of 13.8 +/- 4.7 and 12.5 +/- 3.7 mm from endocardial data. Isopotential maps localized pacing sites with comparable accuracy (14 +/- 5.3 mm). CONCLUSIONS: Body surface potentials and reconstructed epicardial activation patterns during LV pacing correlate well with endocardial data acquired invasively. The exception was during pacing of the septum. Although early results are encouraging, further quantitative data are required to fully validate and apply this noninvasive tool in the clinical arena. |
| | |
Authors:
|
Heather Joanne Shannon; Cesar O Navarro; Bernie A Smith; Anthony J McClelland; Ernest W Lau; Michael J D Roberts; John M C Anderson; Jeninifer A Adgey |
Related Documents
:
|
7787467 - Recent advances in the treatment of acute myocardial infarction. 19575197 - The effect of right ventricular pacing on myocardial oxidative metabolism and efficienc... 8552527 - Successful long-term ventricular pacing via the coronary sinus after the fontan operation. 20888007 - Electrocardiographic characteristics in right ventricular vs biventricular pacing in pa... 1888927 - Serum cholesterol concentration and coronary heart disease in population with low chole... 2070407 - Simplified formula for the calculation of mitral valve area: potential inaccuracies in ... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of electrocardiology Volume: 40 ISSN: 1532-8430 ISO Abbreviation: J Electrocardiol Publication Date: 2007 Nov-Dec |
Date Detail:
|
Created Date: 2007-11-12 Completed Date: 2008-01-07 Revised Date: 2009-11-11 |
Medline Journal Info:
|
Nlm Unique ID: 0153605 Medline TA: J Electrocardiol Country: United States |
Other Details:
|
Languages: eng Pagination: S111-7 Citation Subset: IM |
Affiliation:
|
Regional Medical Cardiology Centre, Royal Victoria Hospital, Belfast, Northern Ireland, United Kingdom. joshannon01@yahoo.co.uk |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Body Surface Potential Mapping / methods* Cardiac Pacing, Artificial / methods* Diagnosis, Computer-Assisted / methods* Diagnostic Imaging / methods* Electrocardiography / methods* Humans Male Middle Aged Ventricular Dysfunction, Left / diagnosis*, prevention & control* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: An algorithm for QT interval monitoring in neonatal intensive care units.
Next Document: Global public health problem of sudden cardiac death.