Document Detail


Activation of fibrinolysis by reinfusion of unwashed salvaged blood after total knee arthroplasty.
MedLine Citation:
PMID:  19932982     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In 19 patients with RA and 20 with OA who underwent autotransfusion with unwashed salvaged blood (USB) after total knee arthroplasty, we performed serial measurement of D-dimer, FgDP, t-PA, and PIC in the plasma and salvaged blood. The PIC level at the completion of salvaged blood transfusion was closely correlated with the volume of USB reinfused in the RA group (p<0.001). The t-PA level of salvaged blood showed a significant positive correlation with the total volume of postoperative drainage in both the RA and OA groups (p<0.05). The increase of total postoperative drainage associated with reinfusion of USB is largely caused by an increase of t-PA in the salvaged blood.
Authors:
Keiji Matsuda; Masahiko Nozawa; Sadanobu Katsube; Katsuhiko Maezawa; Hisashi Kurosawa
Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2009-11-24
Journal Detail:
Title:  Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis     Volume:  42     ISSN:  1473-0502     ISO Abbreviation:  Transfus. Apher. Sci.     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-02-17     Completed Date:  2010-08-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101095653     Medline TA:  Transfus Apher Sci     Country:  England    
Other Details:
Languages:  eng     Pagination:  33-7     Citation Subset:  T    
Copyright Information:
(c) 2009 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Orthopaedics, Juntendo Nerima Hospital, Tokyo, Japan. gozilla@juntendo-nerima.jp
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MeSH Terms
Descriptor/Qualifier:
Aged
Arthritis, Rheumatoid / blood,  surgery
Arthroplasty, Replacement, Knee*
Blood Transfusion, Autologous / adverse effects*,  methods
Female
Fibrin Fibrinogen Degradation Products / analysis
Fibrinogen / analysis
Fibrinolysin / analysis
Fibrinolysis*
Humans
Male
Middle Aged
Osteoarthritis, Knee / blood,  surgery
Plasminogen / analysis
Plasminogen Activator Inhibitor 1 / analysis
Suction
Tissue Plasminogen Activator / analysis
alpha-2-Antiplasmin / analysis
Chemical
Reg. No./Substance:
0/Fibrin Fibrinogen Degradation Products; 0/Plasminogen Activator Inhibitor 1; 0/SERPINE1 protein, human; 0/alpha-2-Antiplasmin; 0/fibrin fragment D; 0/plasmin-plasmin inhibitor complex; 9001-32-5/Fibrinogen; 9001-91-6/Plasminogen; EC 3.4.21.68/Tissue Plasminogen Activator; EC 3.4.21.7/Fibrinolysin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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