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Activated depression: mixed bipolar disorder or agitated unipolar depression?
MedLine Citation:
PMID:  23881708     Owner:  NLM     Status:  In-Data-Review    
The combination of depression and activation presents clinical and diagnostic challenges. It can occur, in either bipolar disorder or major depressive disorder, as increased agitation as a dimension of depression. What is called agitation can consist of expressions of painful inner tension or as disinhibited goal-directed behavior and thought. In bipolar disorder, elements of depression can be combined with those of mania. In this case, the agitation, in addition to increased motor activity and painful inner tension, must include symptoms of mania that are related to goal-directed behavior or manic cognition. These diagnostic considerations are important, as activated depression potentially carries increased behavioral risk, especially for suicidal behavior, and optimal treatments for depressive episodes differ between bipolar disorder and major depressive disorder.
Alan C Swann
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current psychiatry reports     Volume:  15     ISSN:  1535-1645     ISO Abbreviation:  Curr Psychiatry Rep     Publication Date:  2013 Aug 
Date Detail:
Created Date:  2013-07-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888960     Medline TA:  Curr Psychiatry Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  376     Citation Subset:  IM    
Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, 1941 East Road, Room 3216, Houston, TX, 77054, USA,
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