Document Detail

Action of ranitidine on changes in gastric pH during the perioperative period in cardiac surgery
MedLine Citation:
PMID:  3828885     Owner:  NLM     Status:  MEDLINE    
Any state of stress originates a reduction of gastric pH contributing to the development of digestive lesions. The objective of this prospective work was to evaluate in subjects having undergone a heart surgical procedure, the effect of an anti-H2 agent, ranitidine, on the changes with time of gastric pH during the first 24 hours following induced anaesthesia. Administered discontinuously intravenously, ranitidine was shown to have a clearcut effect on gastric pH, shifting the pH profiles towards higher values. This phenomenon proves to be statistically significant from the 12th hour following the beginning of anesthesia.
P Pointaire; V Boggio; A Rerolle; T M Biedzinski; B Caillard
Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Cahiers d'anesthésiologie     Volume:  34     ISSN:  0007-9685     ISO Abbreviation:  Cah Anesthesiol     Publication Date:  1986 Dec 
Date Detail:
Created Date:  1987-05-06     Completed Date:  1987-05-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370650     Medline TA:  Cah Anesthesiol     Country:  FRANCE    
Other Details:
Languages:  fre     Pagination:  681-6     Citation Subset:  IM    
Vernacular Title:
Action de la ranitidine sur l'évolution du pH-gastrique dans la période péri-opératoire de chirurgie cardiaque.
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MeSH Terms
Cardiac Surgical Procedures*
Gastric Acid / secretion*
Gastric Acidity Determination
Middle Aged
Postoperative Complications / prevention & control*
Ranitidine / therapeutic use*
Reg. No./Substance:

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