| Action of nitro- and halophenols upon oxygen consumption and phosphorylation by a cell-free particulate system from arbacia eggs. | |
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MedLine Citation:
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PMID: 15422109 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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1. The ability of 4,6-dinitrocresol and eight other substituted phenols to stimulate oxygen uptake and inhibit phosphorylation by a cell-free particulate system from unfertilized Arbacia eggs has been determined. Five of those agents can produce both stimulation of oxygen consumption and inhibition of phosphorylation; one inhibits both oxygen consumption and phosphorylation; and two have no effect on either oxygen consumption or phosphorylation. In every case the effects of these substituted phenols upon the cell-free particulate systems parallel those upon oxygen consumption and cleavage in the intact fertilized Arbacia eggs. 2. The data suggest that energy for cleavage of the Arbacia egg is provided at least in part by oxidative phosphorylation and that substituted phenols may block cleavage by interfering with generation and transfer of high-energy phosphate groups. |
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Authors:
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G H A CLOWES; A K KELTCH; C F STRITTMATTER; C P WALTERS |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of general physiology Volume: 33 ISSN: 0022-1295 ISO Abbreviation: J. Gen. Physiol. Publication Date: 1950 May |
Date Detail:
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Created Date: 1950-12-01 Completed Date: 2004-09-30 Revised Date: 2011-09-28 |
Medline Journal Info:
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Nlm Unique ID: 2985110R Medline TA: J Gen Physiol Country: Not Available |
Other Details:
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Languages: eng Pagination: 555-61 Citation Subset: OM |
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| MeSH Terms | |
Descriptor/Qualifier:
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Cells* Nitrogen* Nitrogen Compounds* |
| Chemical | |
Reg. No./Substance:
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0/Nitrogen Compounds; 7727-37-9/Nitrogen |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
| Full Text | |
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Journal Information Journal ID (nlm-ta): J Gen Physiol ISSN: 0022-1295 ISSN: 1540-7748 Publisher: The Rockefeller University Press |
Article Information Download PDF  Copyright © Copyright, 1950, by The Rockefeller Institute for Medical Research Received Day: 14 Month: 11 Year: 1949 Print publication date: Day: 20 Month: 5 Year: 1950 Volume: 33 Issue: 5 First Page: 555 Last Page: 561 ID: 2147202 PubMed Id: 15422109 |
| ACTION OF NITRO- AND HALOPHENOLS UPON OXYGEN CONSUMPTION AND PHOSPHORYLATION BY A CELL-FREE PARTICULATE SYSTEM FROM ARBACIA EGGS | |
| G. H. A. Clowes | |
| A. K. Keltch | |
| C. F. Strittmatter | |
| C. P. Walters | |
| From the Lilly Research Laboratories, Indianapolis, Indiana, and the Marine Biological Laboratory, Woods Hole, Massachusetts |
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