Document Detail

Actinomycosis of the neck causing cervical epidural cord compression. 'A case report and review of literature'.
MedLine Citation:
PMID:  17339886     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE AND IMPORTANCE: Involvement of cervical spinal cord by Actinomycosis and consequent cord compression is a rare presentation. As the organism is located in nose and throat, the face and jaw area is commonly affected. Involvement of cervical cord has been rarely recorded. We are reporting this case because of the rarity of area of the involvement and have reviewed literature.
CLINICAL PRESENTATION: A 30-year-old male with multiple discharging sinuses on the nape of neck and upper back for 7 years which resulted in cervical cord compression and spastic paraperesis. Tissue biopsy from the site of discharging sinuses revealed Actinomycosis. Patient responded to the medical therapy with penicillin and power in lower limbs was improved. The local lesion was also reduced.
INTERVENTION: Medical therapy with penicillin and surgical decompression forms the mainstay of treatment.
CONCLUSION: A high degree of suspicion and demonstration of organism by biopsy or culture is essential for treatment. Penicillin is highly effective and should be given for long duration for optimal results.
V Vernon; G Pranav; D Palande
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2007-03-06
Journal Detail:
Title:  Spinal cord     Volume:  45     ISSN:  1362-4393     ISO Abbreviation:  Spinal Cord     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-12-06     Completed Date:  2008-01-23     Revised Date:  2011-06-06    
Medline Journal Info:
Nlm Unique ID:  9609749     Medline TA:  Spinal Cord     Country:  England    
Other Details:
Languages:  eng     Pagination:  787-9     Citation Subset:  IM    
Department of Neurosurgery Grant Medical College and Sir JJ group of Hospitals, Mumbai, India.
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MeSH Terms
Actinomycosis / complications*,  drug therapy,  pathology
Anti-Bacterial Agents / therapeutic use
Antifungal Agents / therapeutic use
Decompression, Surgical
Epidural Space
Erythema / pathology
Magnetic Resonance Imaging
Paraparesis / etiology
Penicillins / therapeutic use
Skin / pathology
Spinal Cord Compression / etiology*,  surgery,  therapy*
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Antifungal Agents; 0/Penicillins

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