| Act your age: Tuning cell behavior to tissue requirements in interfollicular epidermis. | |
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MedLine Citation:
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PMID: 22981943 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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In all tissues the balance of cell proliferation and differentiation needs to be tuned to match the varying requirements of embryonic development and adult life. This is well illustrated by the interfollicular epidermis (IFE), which undergoes expansion and remodeling in utero, significant post natal growth and is then maintained in homeostasis. In addition to sustaining a high daily turnover of cells, the epidermis is able to re-populate areas of tissue damage due to common environmental stresses such as wounding. Here recent insights into proliferating cell behavior in IFE and how this changes through development and into adulthood are discussed. |
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Authors:
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Amit Roshan; Philip H Jones |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-9-7 |
Journal Detail:
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Title: Seminars in cell & developmental biology Volume: - ISSN: 1096-3634 ISO Abbreviation: Semin. Cell Dev. Biol. Publication Date: 2012 Sep |
Date Detail:
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Created Date: 2012-9-17 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9607332 Medline TA: Semin Cell Dev Biol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012. Published by Elsevier Ltd. |
Affiliation:
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Department of Oncology, University of Cambridge, Hutchison/MRC Research Centre, Cambridge CB2 0XZ, UK; Department of Plastic Surgery, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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