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Across breed multi-trait random regression genomic predictions in the Nordic Red dairy cattle.
MedLine Citation:
PMID:  23317061     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The current study evaluates reliability of genomic predictions in selection candidates using multi-trait random regression model, which accounts for interactions between marker effects and breed of origin in the Nordic Red dairy cattle (RDC). The population structure of the RDC is admixed. Data consisted of individual animal breed proportions calculated from the full pedigree, deregressed proofs (DRP) of published estimated breeding values (EBV) for yield traits and genotypic data for 37 595 single nucleotide polymorphic markers. The analysed data included 3330 bulls in the reference population and 812 bulls that were used for validation. Direct genomic breeding values (DGV) were estimated using the model under study, which accounts for breed effects and also with GBLUP, which assume uniform population. Validation reliability was calculated as a coefficient of determination from weighted regression of DRP on DGV (rDRP,DGV 2), scaled by the mean reliability of DRP. Using the breed-specific model increased the reliability of DGV by 2 and 3% for milk and protein, respectively, when compared to homogeneous population GBLUP. The exception was for fat, where there was no gain in reliability. Estimated validation reliabilities were low for milk (0.32) and protein (0.32) and slightly higher (0.42) for fat.
Authors:
M L Makgahlela; E A Mäntysaari; I Strandén; M Koivula; U S Nielsen; M J Sillanpää; J Juga
Publication Detail:
Type:  Journal Article     Date:  2012-07-19
Journal Detail:
Title:  Journal of animal breeding and genetics = Zeitschrift für Tierzüchtung und Züchtungsbiologie     Volume:  130     ISSN:  1439-0388     ISO Abbreviation:  J. Anim. Breed. Genet.     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100955807     Medline TA:  J Anim Breed Genet     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  10-9     Citation Subset:  IM    
Copyright Information:
© 2012 Blackwell Verlag GmbH.
Affiliation:
Department of Agricultural Sciences, University of Helsinki, Helsinki, Finland; MTT Agrifood Research Finland, Biotechnology and Food Research, Biometrical Genetics, Jokioinen, Finland.
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