Document Detail

MedLine Citation:
PMID:  12220276     Owner:  NLM     Status:  MEDLINE    
Acrokeratoelastoidosis of Costa is a rare papular palmoplantar keratosis characterized by small round-oval to rhomboid-shaped, yellowish papules most commonly localized to the palmar surface of the hands and sometimes also found on plantar surfaces of the feet. Both autosomal dominant and sporadic forms of the disease have been reported. Histologically acrokeratoelastoidosis is marked by hyperkeratosis and epidermal hypertrophy. Specific stains for elastic tissue reveal characteristic fragmentation and rarefaction of elastic fibers. We report a sporadic case of acrokeratoelastoidosis in a 13-year-old girl and review the etiology, differential diagnosis, and treatment of this disorder.
Weimin Hu; Thomas F Cook; Gary J Vicki; Dee Anna Glaser
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Pediatric dermatology     Volume:  19     ISSN:  0736-8046     ISO Abbreviation:  Pediatr Dermatol     Publication Date:    2002 Jul-Aug
Date Detail:
Created Date:  2002-09-10     Completed Date:  2002-11-29     Revised Date:  2009-03-03    
Medline Journal Info:
Nlm Unique ID:  8406799     Medline TA:  Pediatr Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  320-2     Citation Subset:  IM    
St. Louis University School of Medicine and Department of Dermatology, Saint Louis University Health Sciences Center, St. Louis, Missouri 63104, USA.
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MeSH Terms
Biopsy, Needle
Dermatologic Agents / therapeutic use
Elastic Tissue / pathology*
Etretinate / therapeutic use
Follow-Up Studies
Keratoderma, Palmoplantar / diagnosis,  drug therapy,  pathology*
Prednisolone / therapeutic use
Risk Assessment
Severity of Illness Index
Reg. No./Substance:
0/Dermatologic Agents; 50-24-8/Prednisolone; 54350-48-0/Etretinate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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