Document Detail

Acrodermatitis chronica atrophicans: a case report and review of the literature.
MedLine Citation:
PMID:  20540415     Owner:  NLM     Status:  MEDLINE    
Acrodermatitis chronica atrophicans (ACA) is a rare tertiary manifestation of Lyme borreliosis, manifesting as inflammatory and atrophic lesions on acral skin. Although ACA rarely has been reported in the United States, it may be seen in approximately 10% of European cases of Lyme borreliosis, most commonly associated with the genospecies Borrelia afzelii. We report a presumptive case of ACA involving an American woman from Pennsylvania with convincing clinical, histopathologic, and serologic findings. We also provide an overview of the history, epidemiology, pathogenesis, clinical and histopathologic presentation, and treatment of ACA.
Matthew T Smetanick; Sharon L Zellis; Tanya Ermolovich
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Cutis     Volume:  85     ISSN:  0011-4162     ISO Abbreviation:  Cutis     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-06-14     Completed Date:  2010-07-22     Revised Date:  2013-09-12    
Medline Journal Info:
Nlm Unique ID:  0006440     Medline TA:  Cutis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  247-52     Citation Subset:  IM    
Department of Dermatology, Philadelphia College of Osteopathic Medicine/Frankford Hospital, Pennsylvania, USA.
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MeSH Terms
Acrodermatitis / diagnosis,  drug therapy,  etiology*
Aged, 80 and over
Anti-Bacterial Agents / therapeutic use
Doxycycline / therapeutic use
Lyme Disease / complications,  diagnosis*,  drug therapy
Reg. No./Substance:
0/Anti-Bacterial Agents; 564-25-0/Doxycycline

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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