Document Detail


Acral mutilation syndrome in a miniature pinscher.
MedLine Citation:
PMID:  20961556     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Acral mutilation syndrome (AMS) is a rare canine hereditary sensory neuropathy that results in progressive mutilation of the distal extremities and which has been reported only in German short-haired pointers, English pointers, English springer spaniels and French spaniels. The present report describes a case of AMS in an 18-month-old female miniature pinscher with progressive self-mutilation of the hind feet. The dog did not respond to any treatment and was humanely destroyed at the age of 30 months. Microscopical findings post mortem were restricted to the nervous system and were compatible with AMS. This is the first case of AMS described in a miniature pinscher. It is not known if the disease was the result of a point mutation in this particular dog or if the miniature pinscher breed will evolve to become a breed predisposed to AMS.
Authors:
M Bardagí; P Montoliu; L Ferrer; D Fondevila; M Pumarola
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Publication Detail:
Type:  Journal Article     Date:  2010-10-18
Journal Detail:
Title:  Journal of comparative pathology     Volume:  144     ISSN:  1532-3129     ISO Abbreviation:  J. Comp. Pathol.     Publication Date:    2011 Feb-Apr
Date Detail:
Created Date:  2011-02-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0102444     Medline TA:  J Comp Pathol     Country:  England    
Other Details:
Languages:  eng     Pagination:  235-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Animal Medicine and Surgery, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain.
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