Document Detail

Acquired von Willebrand Syndrome in a Child Following Berlin Heart EXCOR Pediatric Ventricular Assist Device Implantation: Case Report and Concise Literature Review.
MedLine Citation:
PMID:  25324261     Owner:  NLM     Status:  In-Data-Review    
The development of acquired von Willebrand syndrome (AVWS) after placement of a pulsatile-flow left ventricular assist device (LVAD) is rare and only recently recognized. We report the case of a young infant who was diagnosed with ventricular assist device (VAD)-related AVWS following implantation of a Berlin Heart EXCOR Pediatric Ventricular Assist Device (Berlin Heart Inc., The Woodlands, Texas, USA) for treatment of severe heart failure. Despite significant bleeding, the patient was successfully managed with von Willebrand factor-containing concentrate until VAD explantation led to definitive resolution of the AVWS. This case demonstrates that the possibility of this diagnosis should be considered in pediatric patients when extensive, nonsurgical bleeding is encountered after pulsatile-flow VAD implantation.
John P Costello; Yaser A Diab; Michael Philippe-Auguste; Melissa B Jones; Venkat Shankar; Kenneth D Friedman; Dilip S Nath
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  World journal for pediatric & congenital heart surgery     Volume:  5     ISSN:  2150-136X     ISO Abbreviation:  World J Pediatr Congenit Heart Surg     Publication Date:  2014 Oct 
Date Detail:
Created Date:  2014-10-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101518415     Medline TA:  World J Pediatr Congenit Heart Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  592-8     Citation Subset:  IM    
Copyright Information:
© The Author(s) 2014.
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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