| Acquired ventricular septal defect during acute myocardial infarction: analysis of 38 unoperated necropsy patients and comparison with 50 unoperated necropsy patients without rupture. | |
| | |
MedLine Citation:
|
PMID: 3381755 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Thirty-eight patients (24 men and 14 women) with an acquired ventricular septal defect during acute myocardial infarction (AMI) (rupture group) were studied and their clinical and necropsy findings were compared with 50 patients who died during their first AMI without rupture (nonrupture group). The frequency of systemic hypertension (54 vs 52%), angina pectoris (28 vs 22%) and congestive heart failure (5 vs 0%) before the fatal AMI was similar for both rupture and nonrupture groups. Mean heart weights for men (498 vs 526 g) and women (397 vs 432 g) with and without septal rupture also were insignificantly different. Whereas previous studies of fatal AMI cases have shown that 50% of cases of fatal AMI without rupture have left ventricular scars, only 4 (10%) of the rupture cases had a left ventricular scar before the infarct that ruptured. The rupture group had a significantly more frequent (p less than 0.01) posterior location of the infarcts (74 vs 40%) and, therefore, a higher frequency of associated right ventricular infarcts 50 vs 18%). The number of 3 major (right, left anterior descending and left circumflex) epicardial coronary arteries narrowed at some point greater than 75% in cross-sectional area of atherosclerotic plaque was the same in both groups. The percent of these 3 arteries totally occluded or nearly so (greater than 95% in cross-sectional area) by plaque was significantly less (p less than 0.001) in the rupture group compared with the nonrupture group (9 of 99 arteries [9%] vs 38 of 144 arteries [26%]).(ABSTRACT TRUNCATED AT 400 WORDS) |
| | |
Authors:
|
J M Mann; W C Roberts |
Related Documents
:
|
15996775 - Intracavitary left ventricular hydatid cysts ruptured during cardiopulmonary resuscitat... 18390955 - Intraoperative coronary angiography in postinfarction ventricular free wall rupture: ho... 921445 - Postmyocardial infarction complications requiring surgery. 11175155 - Role of echocardiography in complications associated with partial or complete rupture o... 19857705 - Pivotal karyometric measurements in different types of cardiomyopathic morphology: stud... 23460445 - Caspase-3 activation and increased procollagen type i in irradiated hearts. |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: The American journal of cardiology Volume: 62 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 1988 Jul |
Date Detail:
|
Created Date: 1988-07-25 Completed Date: 1988-07-25 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 8-19 Citation Subset: AIM; IM |
Affiliation:
|
Pathology Branch, National Heart, Lung, and Blood Institute, Bethesda, Maryland 20892. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Aged, 80 and over Coronary Artery Disease / complications, pathology Coronary Vessels / pathology Female Heart Rupture / pathology* Heart Rupture, Post-Infarction / pathology*, surgery Heart Septum / pathology* Humans Male Middle Aged Myocardial Infarction / complications, pathology Myocardium / pathology Organ Size |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Usefulness of the dipyridamole-exercise echocardiography test for diagnosis of coronary artery disea...
Next Document: Predictors of automatic implantable cardioverter defibrillator discharge for life-threatening ventri...