Document Detail

Acquired noncompaction associated with coronary heart disease and myopathy.
MedLine Citation:
PMID:  20457346     Owner:  NLM     Status:  In-Process    
In a 77-year-old man with a history of arterial hypertension, coronary heart disease, dilative cardiomyopathy, mitral and tricuspid insufficiency, arteriovenous block III, implantation of a pacemaker, atrial fibrillation, and heart failure, left ventricular hypertrabeculation (LVHT) was detected on transthoracic echocardiography during hospitalization for worsening heart failure. Revision of previous echocardiography did not show LVHT in any of the previous investigations why LVHT was interpreted as acquired. The additional presentation with bilateral ptosis, madarosis (absent eyelashes), bilateral hypoacusis, sore neck muscles, absent tendon reflexes, weakness for foot extension, ataxic stance, and recurrently elevated creatine kinase with normal troponin-T suggested a metabolic myopathy. Autopsy after death resulting from intractable heart failure, 17 months later, confirmed severe coronary heart disease and LVHT in the apex. The case confirms that LVHT may be acquired in single cases with neuromuscular disease and may represent an adaptive mechanism of an impaired myocardium.
Josef Finsterer; Claudia Stöllberger; Elisabeth Bonner
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-12-11
Journal Detail:
Title:  Heart & lung : the journal of critical care     Volume:  39     ISSN:  1527-3288     ISO Abbreviation:  Heart Lung     Publication Date:    2010 May-Jun
Date Detail:
Created Date:  2010-05-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0330057     Medline TA:  Heart Lung     Country:  United States    
Other Details:
Languages:  eng     Pagination:  240-1     Citation Subset:  AIM; IM    
Copyright Information:
Copyright 2010 Elsevier Inc. All rights reserved.
Krankenanstalt Rudolfstiftung, Vienna, Austria, Europe.
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