Document Detail

Acquired localized cutis laxa confined to the face: case report and review of the literature.
MedLine Citation:
PMID:  15569023     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Cutis laxa is an uncommon entity characterized by laxity of the skin, which hangs in loose folds, producing the appearance of premature aging. It can be subdivided into congenital and acquired. This latter variant is rare and the skin involvement varies from generalized to localized. We report a case of a localized acquired cutis laxa confined to the face, without preceding inflammatory lesions or systemic compromise. Four similar cases have been reported to date. The etiology remains unknown and there is no definitive treatment. METHODS: A 27-year-old White woman came to our hospital with a wrinkled face, pendulous earlobes and drop eyelids. Changes began 5 years prior, and she appeared much older than her age. RESULTS: Histological analysis and ultrastructural examination of skin biopsy revealed reduction and fragmentation of elastic fibers, confirming the diagnosis of cutis laxa. No systemic involvement was diagnosed. The patient was submitted to plastic surgery for repair, with satisfactory results to date. CONCLUSIONS: Acquired localized cutis laxa confined to the face without preceding inflammatory lesions is extremely rare. The etiology remains unknown. Clinical features and histopathologic findings confirm the diagnosis. Surgical repair seems to be the only therapeutic choice, but the results are variable and temporary.
Claudia Jimena Perafán Riveros; Maria Filomena Bejarano Gavilán; Luis Fernando Sayago França; Mírian Nacagami Sotto; Maria Denise Fonseca Takahashi
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  International journal of dermatology     Volume:  43     ISSN:  0011-9059     ISO Abbreviation:  Int. J. Dermatol.     Publication Date:  2004 Dec 
Date Detail:
Created Date:  2004-11-30     Completed Date:  2005-03-10     Revised Date:  2006-10-30    
Medline Journal Info:
Nlm Unique ID:  0243704     Medline TA:  Int J Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  931-5     Citation Subset:  IM    
Hospital das Clínicas da Faculdade de Medicina, University of São Paulo, São Paulo, Brazil.
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MeSH Terms
Cutis Laxa / pathology*
Ear Diseases / pathology
Ear, External / pathology
Elastic Tissue / pathology
Eyelid Diseases / pathology
Facial Dermatoses / pathology*

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