Document Detail

Acquired and inherited thrombophilia disorders in pregnancy.
MedLine Citation:
PMID:  21575801     Owner:  NLM     Status:  In-Data-Review    
Thromboembolism is the leading cause of antepartum and postpartum maternal mortality. The presence of antiphospholipid antibodies is responsible for many pregnancy losses and other morbidities in pregnant women, and is the most prevalent and treatable cause of acquired thrombophilia in pregnancy. There is also evidence that women with thrombophilia are at increased risk not only of pregnancy-related venous thromboembolism but other vascular pregnancy complications. Many studies have examined the association between thrombophilia and pregnancy complications. This article reviews the most up-to-date knowledge of prevalence, pathogenesis, and diagnosis of acquired and inherited thrombophilias and their relationship and association with pregnancy complications.
Silvia S Pierangeli; Benjamin Leader; Giuseppe Barilaro; Rohan Willis; D Ware Branch
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology clinics of North America     Volume:  38     ISSN:  1558-0474     ISO Abbreviation:  Obstet. Gynecol. Clin. North Am.     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-05-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8709551     Medline TA:  Obstet Gynecol Clin North Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  271-95     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Antiphospholipid Standardization Laboratory, Division of Rheumatology, Department of Internal Medicine, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555-0883, USA.
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