Document Detail


Acquired idiopathic generalized anhidrosis: a distinctive clinical syndrome.
MedLine Citation:
PMID:  3065466     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The present study concerns a 28-year-old Japanese man with acquired generalized anhidrosis. The patient's ability to perspire was investigated in an artificial climate room maintained at 40 degrees C and 40% humidity. Although the body temperature rose to 38 degrees C, the patient did not sweat. Neither did sweating occur when the patient was given an intradermal injection of pilocarpine or nicotine. The serum IgE level was elevated. Atrophy and degeneration of the sweat glands, as well as infiltration by lymphocytes and mast cells around the sweat glands, were observed in skin biopsies. Anhidrosis in this patient was suggested to be the result of reduced function of the sweat glands themselves with possible underlying immune-mediated basis.
Authors:
K Murakami; G Sobue; S Terao; T Mitsuma
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Journal of neurology     Volume:  235     ISSN:  0340-5354     ISO Abbreviation:  J. Neurol.     Publication Date:  1988 Sep 
Date Detail:
Created Date:  1989-03-21     Completed Date:  1989-03-21     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0423161     Medline TA:  J Neurol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  428-31     Citation Subset:  IM    
Affiliation:
Fourth Department of Internal Medicine, Aichi Medical University, Aichi-ken, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Humans
Hypohidrosis / diagnosis,  pathology,  physiopathology*
Male
Skin / pathology
Sweat Glands / pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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