| Acquired hemophilia in a patient with systemic lupus erythematosus: a case report and literature review. | |
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MedLine Citation:
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PMID: 18551353 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report the case of a 38-year-old female patient with systemic lupus erythematosus (SLE) who developed acquired hemophilia caused by factor VIII (FVIII) inhibitors. She manifested spontaneous bleeding symptoms such as ecchymoses and hematuria. Laboratory findings showed an isolated prolongation of the activated partial thromboplastin time, reduced FVIII activity, and a high titer of FVIII inhibitors. She was successfully treated with oral predonisolone and cyclosporine in combination with steroid and cyclophosphamide pulse therapy. |
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Authors:
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Mitsuteru Akahoshi; Kumiko Aizawa; Shuji Nagano; Hisako Inoue; Atsushi Sadanaga; Yojiro Arinobu; Hiroaki Niiro; Hitoshi Nakashima |
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Publication Detail:
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Type: Case Reports; Journal Article; Review Date: 2008-06-13 |
Journal Detail:
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Title: Modern rheumatology / the Japan Rheumatism Association Volume: 18 ISSN: 1439-7595 ISO Abbreviation: Mod Rheumatol Publication Date: 2008 |
Date Detail:
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Created Date: 2008-10-06 Completed Date: 2009-04-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100959226 Medline TA: Mod Rheumatol Country: Japan |
Other Details:
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Languages: eng Pagination: 511-5 Citation Subset: IM |
Affiliation:
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Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, and Department of Internal Medicine, Chihaya Hospital, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan. akahoshi@intmed1.med.kyushu-u.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Autoantibodies / immunology* Ecchymosis / etiology Factor VIII / immunology* Female Hemophilia A / complications, immunology* Humans Lupus Erythematosus, Systemic / complications, immunology* |
| Chemical | |
Reg. No./Substance:
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0/Autoantibodies; 9001-27-8/Factor VIII |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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