Document Detail

Acquired haemophilia heralded by bleeding into the oral mucosa in a patient with bullous pemphigoid, rheumatoid arthritis, and vitiligo.
MedLine Citation:
PMID:  16397069     Owner:  NLM     Status:  MEDLINE    
Acquired haemophilia is rare and potentially fatal, with a mortality of 20% if left untreated. There is a strong association with other autoimmune diseases. This report describes a patient with rheumatoid arthritis, vitiligo, and bullous pemphigoid where the diagnosis of acquired haemophilia was made after an extensive bleed into a bullous lesion in the buccal mucosa. This case highlights some of the potential complications of acquired haemophilia and its treatment.
R S Patel; K E Harman; C Nichols; R M Burd; S Pavord
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Postgraduate medical journal     Volume:  82     ISSN:  1469-0756     ISO Abbreviation:  Postgrad Med J     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2006-01-06     Completed Date:  2006-07-21     Revised Date:  2013-06-07    
Medline Journal Info:
Nlm Unique ID:  0234135     Medline TA:  Postgrad Med J     Country:  England    
Other Details:
Languages:  eng     Pagination:  e3     Citation Subset:  IM    
Department of Haemostasis and Thrombosis, Directorate of Haematology, Leicester Royal Infirmary, Leicester LE1 5WW, UK.
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MeSH Terms
Arthritis, Rheumatoid / complications*
Hemophilia A / drug therapy,  etiology*
Mouth Mucosa
Oral Hemorrhage / etiology*
Pemphigoid, Bullous / complications*
Vitiligo / complications*

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