Document Detail


Acquired haemoglobin H disease associated with myelodysplastic syndrome.
MedLine Citation:
PMID:  19032897     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 60-year-old male patient presented with jaundice. Initial investigations showed anemia, indirect hyperbilirubinemia, raised Lactic Dehydrogenase (LDH) and increased reticulocyte count suggestive of hemolysis. Considering hemolysis low MCV and basophilic stippling on peripheral film, hemoglobin electrophoresis was done that showed Haemoglobin H (15.5%) that in the absence of family history was thought to be acquired. After bone marrow examination, the final diagnosis was Myelodysplastic Syndrome (MDS), Refractory anemia with excess of blast (RAEB) associated with acquired Haemoglobin H (Hb H) disease.
Authors:
Syed Qamar Abbas; Nasiruddin; Mohammed Misfer Al-Gethami
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the College of Physicians and Surgeons--Pakistan : JCPSP     Volume:  18     ISSN:  1022-386X     ISO Abbreviation:  J Coll Physicians Surg Pak     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-11-26     Completed Date:  2009-03-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9606447     Medline TA:  J Coll Physicians Surg Pak     Country:  Pakistan    
Other Details:
Languages:  eng     Pagination:  784-6     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, Armed Forces Hospital, Sharourah, Kingdom of Saudi Arabia. qamarchk@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Humans
Male
Middle Aged
Myelodysplastic Syndromes / complications*
alpha-Thalassemia / etiology*

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