Document Detail

Acquired dermal melanocytosis of the hand at the site of treated psoriasis.
MedLine Citation:
PMID:  20040252     Owner:  NLM     Status:  MEDLINE    
Dermal melanocytosis is a benign phenomenon most commonly noted in people with darkly pigmented skin. Multiple entities with dermal melanocytosis are described, including Mongolian spot, nevus of Ota, nevus of Ito, nevus of Hori, and acquired dermal melanocytosis. We report a case of acquired dermal melanocytosis occurring in a 42-year-old Hispanic man with psoriasis treated with infliximab for 9 months. The patient presented with an isolated pigmented patch on his left dorsal hand. Histopathologic examination of the skin revealed numerous dendritic, heavily pigmented melanocytes in the papillary and upper reticular dermis. We review the literature and discuss the pathogenesis of acquired dermal melanocytosis.
Brian P Kelley; Sean D Doherty; Antoanella Calame; Sylvia Hsu
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-12-15
Journal Detail:
Title:  Dermatology online journal     Volume:  15     ISSN:  1087-2108     ISO Abbreviation:  Dermatol. Online J.     Publication Date:  2009  
Date Detail:
Created Date:  2009-12-30     Completed Date:  2010-03-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610776     Medline TA:  Dermatol Online J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2     Citation Subset:  IM    
Department of Dermatology, Baylor College of Medicine, Houston, Texas, USA.
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MeSH Terms
Hyperpigmentation / etiology,  pathology*
Psoriasis / therapy

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