Document Detail

Acquired cutis laxa in a 55-year-old female with multiple myeloma and serologic evidence of systemic lupus erythematosus.
MedLine Citation:
PMID:  21810393     Owner:  NLM     Status:  In-Data-Review    
Cutis laxa (CL) is a rare connective tissue disorder characterized by loosely hanging skin folds. Histopathology reveals degenerative changes in the dermal elastic fibers, although loss of elastin can also occur in alveolar walls, blood vessels, and other organs. The coexistence of autoimmune diseases and monoclonal gammopathies is rare but well documented in the literature. Here we report an unusual case of cutis laxa (CL) preceding the development of serologic evidence of systemic lupus erythematosus (SLE) and a diagnosis of multiple myeloma (MM) by seven and eleven years respectively.
Dennis P Kim; Peter A Klein
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Publication Detail:
Type:  Journal Article     Date:  2011-07-15
Journal Detail:
Title:  Dermatology online journal     Volume:  17     ISSN:  1087-2108     ISO Abbreviation:  Dermatol. Online J.     Publication Date:  2011  
Date Detail:
Created Date:  2011-08-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610776     Medline TA:  Dermatol Online J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  8     Citation Subset:  IM    
School of Medicine, Stony Brook University, Stony Brook, New York.
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