Document Detail

Acquired aortic regurgitation after coil occlusion of patent ductus arteriosus.
MedLine Citation:
PMID:  15490034     Owner:  NLM     Status:  MEDLINE    
Some patients with patent ductus arteriosus (PDA) may develop new aortic regurgitation (AR) after coil occlusion. This study evaluated the risk factors for the development of AR after coil occlusion of PDA. A total of 23 patients with PDA were managed with coil embolization over a three-and-a-half-year period. Three patients with pre-embolization AR were excluded. A post-occlusion transthoracic echocardiogram was performed within 24 hours after the procedure. Ten patients developed AR and 10 did not. Gender, age, weight, body surface area (BSA), pulmonary artery pressure, and pulmonary vascular resistance did not differ significantly between the 2 groups. Both larger PDA size (either corrected for weight or BSA, p = 0.008 and 0.002, respectively) and a higher ratio of pulmonary to systemic flow (Qp/Qs) [p = 0.013] were significant risk factors for the development of AR after coil occlusion. Re-evaluation of the patients at 3 and 6 months after the procedure revealed 7 patients still had a regurgitant jet. The results of this study suggest that the larger the PDA and larger the shunt, the greater the likelihood of developing AR after coil occlusion.
Chang-Hsien Yu; Ming-Ren Chen; Haw-Kwei Hwang; Shye-Jao Wu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the Formosan Medical Association = Taiwan yi zhi     Volume:  103     ISSN:  0929-6646     ISO Abbreviation:  J. Formos. Med. Assoc.     Publication Date:  2004 Oct 
Date Detail:
Created Date:  2004-10-18     Completed Date:  2005-02-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9214933     Medline TA:  J Formos Med Assoc     Country:  China    
Other Details:
Languages:  eng     Pagination:  803-5     Citation Subset:  IM    
Department of Pediatrics, Mackay Memorial Hospital Taipei, Taiwan.
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MeSH Terms
Aortic Valve Insufficiency / etiology*
Child, Preschool
Ductus Arteriosus, Patent / pathology,  therapy*
Embolization, Therapeutic / adverse effects*,  instrumentation
Pulmonary Circulation
Risk Factors

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