Document Detail

Acquired Long QT Syndrome: Frequency, Onset, and Risk Factors in Intensive Care Patients.
MedLine Citation:
PMID:  23027789     Owner:  NLM     Status:  In-Data-Review    
Background Acquired long QT syndrome is a reversible condition that can lead to torsades de pointes and sudden cardiac death. Objective To determine the frequency, onset, frequency of medications, and risk factors for the syndrome in intensive care patients. Methods In a retrospective chart review of 88 subjects, hourly corrected QT intervals calculated by using the Bazett formula were collected. Acquired long QT syndrome was defined as a corrected QT of 500 milliseconds or longer or an increase in corrected QT of 60 milliseconds or greater from baseline level. Risk factors and medications administered were collected from patients' medical records. Results The syndrome occurred in 46 patients (52%); mean time of onset was 7.4 hours (SD, 9.4) from time of admission. Among the 88 patients, 52 (59%) received a known QTc-prolonging medication. Among the 46 with the syndrome, 23 (50%) received a known QT-prolonging medication. No other risk factor studied was significantly predictive of the syndrome. Conclusions Acquired long QT syndrome occurs in patients not treated with a known QT-prolonging medication, indicating the importance of frequent QT monitoring of all intensive care patients.
Teri M Kozik; Shu-Fen Wung
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Critical care nurse     Volume:  32     ISSN:  1940-8250     ISO Abbreviation:  Crit Care Nurse     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8207799     Medline TA:  Crit Care Nurse     Country:  United States    
Other Details:
Languages:  eng     Pagination:  32-41     Citation Subset:  N    
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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