Document Detail


Acquired factor VIII and von Willebrand factor (aFVIII/VWF) deficiency and hypothyroidism in a case with hypopituitarism.
MedLine Citation:
PMID:  18550587     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This article reports a female who presented with bleeding, acquired factor VIII and von Willebrand factor (aFVIII-VWF) deficiency, and central deficiency in the thyroid and adrenal axis (Sheehan's syndrome). After starting hormone replacement therapy, relief of bleeding manifestations was associated with correction of both FVIII and VWF to normal. This report draws attention to a rare association between the acquired form of von Willebrand disease and hypothyroidism of central origin.
Authors:
Miriam C Oliveira; Caroline K Kramer; Caroline P Marroni; Carolina G S Le?es; Luciana Viana; S?rgio Roithman; Alexandre Schmaedecke; J?lia F S Pereira-Lima
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-06-11
Journal Detail:
Title:  Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis     Volume:  16     ISSN:  1938-2723     ISO Abbreviation:  Clin. Appl. Thromb. Hemost.     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-01-22     Completed Date:  2010-03-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9508125     Medline TA:  Clin Appl Thromb Hemost     Country:  United States    
Other Details:
Languages:  eng     Pagination:  107-9     Citation Subset:  IM    
Affiliation:
Discipline of Endocrinology, Universidade Federal de Ci?ncias da Sa?de de Porto Alegre (UFCSPA), Brasil. mco@portoweb.com.br
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MeSH Terms
Descriptor/Qualifier:
Adult
Factor VIII / metabolism
Female
Hemophilia A / etiology*
Hemorrhage / blood,  etiology*
Humans
Hypothyroidism / blood,  complications*
von Willebrand Diseases / etiology*
von Willebrand Factor / metabolism
Chemical
Reg. No./Substance:
0/von Willebrand Factor; 9001-27-8/Factor VIII

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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