Document Detail


Acoustical nanometre-scale vibrations of live cells detected by a near-field optical setup.
MedLine Citation:
PMID:  19532815     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The Scanning Near-field Optical Microscope (SNOM) is able to detect tiny vertical movement on the cell membrane in the range of only 1 nanometer or less, about 3 orders of magnitude better than conventional optical microscopes. Here we show intriguing data of cell membrane nanometer-scale dynamics associated to different phenomena of the cell's The Scanning Near-field Optical Microscope (SNOM) is able to detect tiny vertical movement on the cell membrane in the range of only 1 nanometer or less, about 3 orders of magnitude better than conventional optical microscopes. Here we show intriguing data of cell membrane nanometer-scale dynamics associated to different phenomena of the cell's life, such as cell cycle and cell death, on rat pheochromocytoma line PC12. Working in culture medium with alive and unperturbed samples, we could detect nanometer-sized movements; Fourier components revealed a clear distinct behavior associated to regulation of neurite outgrowth and changes on morphology after necrotic stimulus.
Authors:
Rosaria Piga; Ruggero Micheletto; Yoichi Kawakami
Related Documents :
15817275 - Simvastatin treatment does not protect retinal ganglion cells from degeneration in a ra...
18634795 - Characterization of pdf-immunoreactive neurons in the optic lobe and cerebral lobe of t...
8361645 - Target cells for the isthmo-optic fibers in the retina of the japanese quail.
9473325 - Pax2 expression and retinal morphogenesis in the normal and krd mouse.
19788345 - Development of a new assay system for evaluating the permeability of various substances...
21206005 - Expression of her2 in colorectal cancer does not correlate with prognosis.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Optics express     Volume:  15     ISSN:  1094-4087     ISO Abbreviation:  Opt Express     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2009-06-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101137103     Medline TA:  Opt Express     Country:  United States    
Other Details:
Languages:  eng     Pagination:  5589-94     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Rayleigh-Gans scattering approximation: surprisingly useful for understanding backscattering from di...
Next Document:  Highly sensitive spectroscopic detection of heme-protein submonolayer films by channel integrated op...