Document Detail

Acoustic analysis of autologous fat injection versus thyroplasty in the same patient.
MedLine Citation:
PMID:  14653369     Owner:  NLM     Status:  MEDLINE    
We objectively measured the acoustic effects of treatment of unilateral vocal fold paralysis by injection of autologous fat and by polytetrafluoroethylene thyroplasty, in the same patient. To our knowledge, this is the first report comparing the two techniques by using the patient's normal voice as the control. The voice of a male patient was recorded before and after onset of unilateral vocal fold paralysis, after treatment with autologous fat, and after polytetrafluoroethylene thyroplasty. Acoustic analysis was performed on a long-term average spectrum of text and on the MDVP (Kay Elemetrics) evaluation of the vowel /a/. Jitter and shimmer were not normalized, but they improved to a greater extent after fat injection. The cepstral peak prominence, spectral skewness, and long-term average spectrum returned to preparalytic values after both treatments, but improved to a greater extent after fat injection. This study showed that both techniques can return the voice to preparalytic values. Spectral measurements best reflected the voice improvement. Further prospective studies in a larger number of patients will be necessary to confirm these results and to determine the long-term objective voice outcome obtained with these techniques.
Dana M Hartl; Jacqueline Vaissière; Ollivier Laccourreye; Daniel F Brasnu
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Annals of otology, rhinology, and laryngology     Volume:  112     ISSN:  0003-4894     ISO Abbreviation:  Ann. Otol. Rhinol. Laryngol.     Publication Date:  2003 Nov 
Date Detail:
Created Date:  2003-12-04     Completed Date:  2003-12-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0407300     Medline TA:  Ann Otol Rhinol Laryngol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  987-92     Citation Subset:  AIM; IM    
Voice, Biomaterials, and Head and Neck Oncology Research Laboratory, University Paris V, Hôpital Européen Georges Pompidou, Paris, France.
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MeSH Terms
Adipose Tissue / transplantation*
Polytetrafluoroethylene / administration & dosage
Prospective Studies
Speech Acoustics*
Thyroid Cartilage / surgery*
Vocal Cord Paralysis / surgery*
Reg. No./Substance:

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