Document Detail


Acoustic airway profiles in unilateral cleft palate patients.
MedLine Citation:
PMID:  10499405     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: This study investigates the nasal airway in unilateral cleft palate patients by means of a noninvasive, objective diagnostic method that provides topographic information about the airway profile. DESIGN: A consecutive sample of patients was measured. SETTING: Cleft palate rehabilitation center of the University of Mainz, Germany. PATIENTS: Forty-nine subjects were investigated: 34 full-grown patients with complete unilateral cleft lip and palate and 15 controls with subjective normal nasal patency. INTERVENTION: A transnasal series of three acoustic measurements of nasal volume was performed per nostril; measurements were taken both before and after decongestion with 0.3 mg xylometazoline per nostril. Minimum cross-sectional area, nasal volume, and decongestion capacity were calculated for both the cleft side and the contralateral side and for both nasal sides in controls. RESULTS: Pathologic obstructions (<0.4 cm2) were detected on the cleft side in 75% of patients but were detected in only 15% of patients on the contralateral side (p < .001). The valve area of the cleft side (0.32 +/- 0.2 cm2) yielded significantly (p < .001) lower cross-sectional values compared with the contralateral side (0.56 +/- 0.1 cm2). Total nasal volume was determined to be 35% smaller on the cleft side (p < .001). Significantly higher decongestion capacity was verified on the cleft side, thus indicating mucosal hypertrophy. CONCLUSION: Despite a wide range of interindividual variability, we recognized a characteristic "descending W"" airway pattern in cleft palate patients. Acoustic rhinometry seems to be a powerful tool for acquiring topographic information about the individual airway profile. It has proven helpful in visualizing the location and amount of pathologic obstructions, rendering it especially useful for preoperative investigation and quality control in corrective cleft nose surgery.
Authors:
M Kunkel; U Wahlmann; W Wagner
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association     Volume:  36     ISSN:  1055-6656     ISO Abbreviation:  Cleft Palate Craniofac. J.     Publication Date:  1999 Sep 
Date Detail:
Created Date:  1999-11-12     Completed Date:  1999-11-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9102566     Medline TA:  Cleft Palate Craniofac J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  434-40     Citation Subset:  D; IM    
Affiliation:
Department of Oral and Maxillofacial Surgery, University of Mainz, Germany.
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MeSH Terms
Descriptor/Qualifier:
Acoustics
Adolescent
Adult
Biophysics / statistics & numerical data
Cleft Palate / physiopathology*,  surgery
Humans
Imidazoles / therapeutic use
Nasal Cavity / drug effects,  physiopathology*
Nasal Decongestants / therapeutic use
Nasal Obstruction / drug therapy,  physiopathology
Nose / abnormalities
Statistics, Nonparametric
Chemical
Reg. No./Substance:
0/Imidazoles; 0/Nasal Decongestants; 526-36-3/xylometazoline

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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