| Acoustic radiation force impulse imaging on ex vivo abdominal aortic aneurysm model. | |
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MedLine Citation:
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PMID: 20381946 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A method for reliable, noninvasive estimation of abdominal aortic aneurysms (AAA) wall mechanics may be a useful clinical tool for rupture prediction. An in vitro AAA model was developed from an excised porcine aorta with elastase treatment. The AAA model behaviour was analysed using acoustic radiation force impulse (ARFI) imaging techniques to generate and measure wave propagation in both aneurysmal and normal aortic tissue. Opening angle measurement showed a fourfold decrease from healthy aorta to AAA model and pathologic analysis verified this elastin degradation. Maximum wave velocity at 180 mm Hg was 7 mm/ms for healthy tissue and 8.26 mm/ms for the aneurysmal tissue. The mechanical changes produced in the artificially induced aneurysm were found to be detectable using ARFI imaging. |
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Authors:
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Aine P Tierney; Douglas M Dumont; Anthony Callanan; Gregg E Trahey; Timothy M McGloughlin |
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Publication Detail:
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Type: Evaluation Studies; In Vitro; Journal Article; Research Support, Non-U.S. Gov't Date: 2010-04-09 |
Journal Detail:
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Title: Ultrasound in medicine & biology Volume: 36 ISSN: 1879-291X ISO Abbreviation: Ultrasound Med Biol Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-04-27 Completed Date: 2010-08-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0410553 Medline TA: Ultrasound Med Biol Country: England |
Other Details:
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Languages: eng Pagination: 821-32 Citation Subset: IM |
Copyright Information:
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Copyright 2010 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Materials and Surface Science Institute, University of Limerick, Limerick, Ireland. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Algorithms* Animals Aorta, Abdominal / ultrasonography* Aortic Aneurysm, Abdominal / ultrasonography* Disease Models, Animal* Elasticity Imaging Techniques / methods* Humans Image Enhancement / methods Image Interpretation, Computer-Assisted / methods* Reproducibility of Results Sensitivity and Specificity Swine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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