Document Detail

Acne vulgaris in childhood. Pathogenesis and management.
MedLine Citation:
PMID:  2941198     Owner:  NLM     Status:  MEDLINE    
Acne vulgaris is a common skin disorder. Although it is most prevalent in the second decade of life, its beginnings are heralded by increased activity of the sebaceous glands and faulty follicular keratinization, which are already evident in mid to late childhood. The subsequent and increasing proliferation of the follicular anaerobic diphtheroid microflora contribute further as an important pathogenic factor in the generation of inflammatory lesions. Treatments of acne, therefore, are aimed at reducing the follicular anaerobic bacteria, counteracting the follicular hyperkeratosis, and inhibiting the activity of sebaceous glands.
D M Yonkosky; P E Pochi
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Dermatologic clinics     Volume:  4     ISSN:  0733-8635     ISO Abbreviation:  Dermatol Clin     Publication Date:  1986 Jan 
Date Detail:
Created Date:  1986-08-18     Completed Date:  1986-08-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8300886     Medline TA:  Dermatol Clin     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  127-36     Citation Subset:  IM    
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MeSH Terms
Acne Vulgaris / drug therapy,  etiology*
Anti-Bacterial Agents / therapeutic use
Anti-Infective Agents, Local / therapeutic use
Bacterial Infections / etiology
Benzoyl Peroxide / therapeutic use
Child, Preschool
Infant, Newborn
Keratosis / etiology
Propionibacterium acnes
Sebaceous Glands / microbiology,  secretion
Sebum / secretion
Tretinoin / therapeutic use
Triamcinolone Acetonide / therapeutic use
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Anti-Infective Agents, Local; 302-79-4/Tretinoin; 4759-48-2/Isotretinoin; 76-25-5/Triamcinolone Acetonide; 94-36-0/Benzoyl Peroxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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