Document Detail


Acidic glycosaminoglycans in human esophagus tissue.
MedLine Citation:
PMID:  375464     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The constitution of acidic glycosaminoglycans (AGAG) in the normal human esophagi which were obtained at autopsy from 13 female subjects, from 30 to 59 years old, was biochemically analyzed by the procedures such as resin chromatographic separation, electrophoretic characterization in 3 buffer systems and enzymic assay with chondroitinases and hyaluronidase. The main AGAG was hyaluronic acid which amounts to a half of total AGAG, followed by heparan sulfates and dermatan sulfate one fifth of total AGAG each, and small amounts of chondroitin-4- and -6-sulfates and oversulfated chondroitin sulfate. Heparin was not detected. A possible role of the esophageal AGAG was discussed.
Authors:
T Sekino; K Murata; Y Saito
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Tohoku journal of experimental medicine     Volume:  127     ISSN:  0040-8727     ISO Abbreviation:  Tohoku J. Exp. Med.     Publication Date:  1979 Mar 
Date Detail:
Created Date:  1979-07-28     Completed Date:  1979-07-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0417355     Medline TA:  Tohoku J Exp Med     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  273-80     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Chemical Fractionation
Chromatography
Dermatan Sulfate / analysis
Electrophoresis
Esophagus / analysis*
Female
Glycosaminoglycans / analysis*
Heparitin Sulfate / analysis
Humans
Hyaluronic Acid / analysis
Immunoenzyme Techniques
Middle Aged
Chemical
Reg. No./Substance:
0/Glycosaminoglycans; 24967-94-0/Dermatan Sulfate; 9004-61-9/Hyaluronic Acid; 9050-30-0/Heparitin Sulfate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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