Document Detail


Acidic glycosaminoglycans in cultured skin fibroblasts of a patient with epidermolysis bullosa dystrophica dominans.
MedLine Citation:
PMID:  7385228     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A biochemical study was carried out on acidic glycosaminoglycans in the cultured skin fibroblasts obtained from a patient with epidermolysis bullosa dystrophica dominans. Acidic glycosaminoglycans were separated from fibroblasts and medium, and subjected to quantiative and qualitative analyses by cellulose acetate membrane electrophoresis, column chromatography and gel filtration. It was found that hyaluronic acid and dermatan sulfate were slightly increased in epidermolysis bullosa dystrophica dominans in comparison with the normal control.
Authors:
M Igarashi; M Seiji
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Tohoku journal of experimental medicine     Volume:  130     ISSN:  0040-8727     ISO Abbreviation:  Tohoku J. Exp. Med.     Publication Date:  1980 Feb 
Date Detail:
Created Date:  1980-08-25     Completed Date:  1980-08-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0417355     Medline TA:  Tohoku J Exp Med     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  207-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Cells, Cultured
Epidermolysis Bullosa / metabolism*,  pathology
Fibroblasts / analysis
Glycosaminoglycans / analysis*
Humans
Skin / analysis*
Chemical
Reg. No./Substance:
0/Glycosaminoglycans

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