| Acid trehalase is involved in intracellular trehalose mobilization during postdiauxic growth and severe saline stress in Saccharomyces cerevisiae. | |
| | |
MedLine Citation:
|
PMID: 19016884 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The role of the acid trehalase encoded by the ATH1 gene in the yeast Saccharomyces cerevisiae is still unclear. In this work, we investigated the regulation of ATH1 transcription and found a clear involvement of the protein kinase Hog1p in the induction of this gene under severe stress conditions, such as high salt. We also detected changes in the acid trehalase activity and trehalose levels, indicating a role of the acid trehalase in intracellular trehalose mobilization. Finally, the growth analysis for different mutants in neutral and acid trehalases after high salt stress implicates acid trehalase activity in saline stress resistance. |
| | |
Authors:
|
Elena Garre; Roberto Pérez-Torrado; José V Gimeno-Alcañiz; Emilia Matallana |
Related Documents
:
|
22981274 - Benzoic acid and specific 2-oxo acids activate hepatic efflux of glutamate at oat2. 6426504 - Activation of an erythrocyte nad:arginine adp-ribosyltransferase by lysolecithin and no... 994314 - The long-term hemodynamic effect of fusaric acid in elderly hypertensive patients. 17046244 - Boron impregnation treatment of eucalyptus grandis wood. 3090234 - Mechanism of action and structural requirements of vasopressin analog inhibition of tra... 12069534 - Clinical approach to inherited metabolic disorders in neonates: an overview. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2008-11-05 |
Journal Detail:
|
Title: FEMS yeast research Volume: 9 ISSN: 1567-1364 ISO Abbreviation: FEMS Yeast Res. Publication Date: 2009 Feb |
Date Detail:
|
Created Date: 2009-01-09 Completed Date: 2009-03-06 Revised Date: 2009-11-19 |
Medline Journal Info:
|
Nlm Unique ID: 101085384 Medline TA: FEMS Yeast Res Country: England |
Other Details:
|
Languages: eng Pagination: 52-62 Citation Subset: IM |
Affiliation:
|
Departamento de Bioquímica y Biología Molecular, Universitat de València, Valencia, Spain. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Gene Deletion Gene Expression Profiling Gene Expression Regulation, Fungal Mitogen-Activated Protein Kinases / metabolism Osmotic Pressure Saccharomyces cerevisiae / enzymology*, growth & development, physiology Saccharomyces cerevisiae Proteins / genetics, metabolism* Salinity Transcription, Genetic Trehalase / genetics, metabolism* Trehalose / metabolism* |
| Chemical | |
Reg. No./Substance:
|
0/Saccharomyces cerevisiae Proteins; 99-20-7/Trehalose; EC 2.7.10.-/HOG1 protein, S cerevisiae; EC 2.7.11.24/Mitogen-Activated Protein Kinases; EC 3.2.1.28/ATH1 protein, S cerevisiae; EC 3.2.1.28/Trehalase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Engineering prokaryotic gene circuits.
Next Document: Improved gene disruption method for Torulaspora delbrueckii.