Document Detail

Acid phosphatase in squamous cell carcinoma.
MedLine Citation:
PMID:  582368     Owner:  NLM     Status:  MEDLINE    
Surgical specimens of oral squamous cell carcinoma were processed for cytochemistry of acid phosphatase using Gomori's substrate. Reaction product was deposited in the cytoplasmic dense bodies, autophagic vacuoles, cytoplasmic projections, and advancing cell borders. Results of this study suggest that acid phosphatase and its associated lysosomes seem to play a role in the invasiveness of cancer cells.
S Y Chen; R Harwick
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Archives of pathology & laboratory medicine     Volume:  103     ISSN:  0003-9985     ISO Abbreviation:  Arch. Pathol. Lab. Med.     Publication Date:  1979 Sep 
Date Detail:
Created Date:  1979-09-27     Completed Date:  1979-09-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7607091     Medline TA:  Arch Pathol Lab Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  531-3     Citation Subset:  AIM; IM    
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MeSH Terms
Acid Phosphatase / metabolism*
Carcinoma, Squamous Cell / enzymology*,  ultrastructure
Lysosomes / enzymology
Middle Aged
Mouth Neoplasms / enzymology*,  ultrastructure
Reg. No./Substance:
EC Phosphatase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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