Document Detail

Acid hydrolases in blister fluid. 4. Influence of ultraviolet radiation.
MedLine Citation:
PMID:  678465     Owner:  NLM     Status:  MEDLINE    
Large, dose-related increases have been demonstrated in the activity of lysosomal hydrolases in the fluid of experimental suction blisters raised on skin previously irradiated with UVR-B. These increases appear after a latent period of 11--18 h, and the pattern of changes shows an extremely good correlation with the hydrolase profile of epidermis. These observations offer strong support for the concept that lysosomes participated in the sequence of events following UV irradiation, but seem to rule out the lysosome as the initial target for UVR.
G Volden
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The British journal of dermatology     Volume:  99     ISSN:  0007-0963     ISO Abbreviation:  Br. J. Dermatol.     Publication Date:  1978 Jul 
Date Detail:
Created Date:  1978-10-25     Completed Date:  1978-10-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0004041     Medline TA:  Br J Dermatol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  53-60     Citation Subset:  IM    
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MeSH Terms
Blister / enzymology*
Dose-Response Relationship, Radiation
Exudates and Transudates / enzymology
Hydrolases / metabolism*
Middle Aged
Skin / radiation effects*
Ultraviolet Rays*
Reg. No./Substance:
EC 3.-/Hydrolases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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