Document Detail

Acid gastroesophageal reflux and symptom occurrence. Analysis of some factors influencing their association.
MedLine Citation:
PMID:  2598756     Owner:  NLM     Status:  MEDLINE    
In 17 patients with esophagitis (degree I = erythema, N = 10; degree II = erosions, N = 7) esophageal pH was measured at 5 and 10 cm above the esophagogastric junction to assess whether the extension of acid reflux and the severity of the mucosal lesions could influence the association between reflux and symptoms. A minority of the refluxes were related with symptoms (4.0% and 7.7% in degree I, 14.1% and 12.0% in degree II at 5 and 10 cm respectively), whereas 65.4% and 100% of the symptoms were related with reflux in degrees I and II, respectively, with 76.5% and 35.7% occurring during refluxes reaching the proximal recording site. A relationship of symptoms with reflux is shown, particularly in erosive disease. Some reflux characteristics (extension, duration, acidity) seem to influence symptom occurrence mainly in mild esophagitis; however, more than 85% of the acid reflux episodes are symptom-free, regardless of the severity of the mucosal injury.
F Baldi; F Ferrarini; A Longanesi; M Ragazzini; L Barbara
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Digestive diseases and sciences     Volume:  34     ISSN:  0163-2116     ISO Abbreviation:  Dig. Dis. Sci.     Publication Date:  1989 Dec 
Date Detail:
Created Date:  1990-01-30     Completed Date:  1990-01-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7902782     Medline TA:  Dig Dis Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1890-3     Citation Subset:  AIM; IM    
Department of Internal Medicine and Gastroenterology of the University, Policlinico S. Orsola, Bologna, Italy.
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MeSH Terms
Electrodes, Implanted
Esophagitis, Peptic / etiology*
Gastroesophageal Reflux / complications*,  diagnosis
Hydrogen-Ion Concentration
Middle Aged
Monitoring, Physiologic
Time Factors

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