| Acid-degradable solid-walled microcapsules for pH-responsive burst-release drug delivery. | |
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MedLine Citation:
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PMID: 21113530 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Acid-degradable microcapsules were prepared via an interfacial polymerization. Degradation of the thin wall of the capsules leads to all-or-nothing cargo release. The only byproducts of degradation are acetone, and a non-toxic triamide. Proof-of-concept experiments showed that cargo can be delivered to and released in cells. |
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Authors:
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Kyle E Broaders; Stefan J Pastine; Sirisha Grandhe; Jean M J Fréchet |
Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S. Date: 2010-11-26 |
Journal Detail:
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Title: Chemical communications (Cambridge, England) Volume: 47 ISSN: 1364-548X ISO Abbreviation: Chem. Commun. (Camb.) Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2010-12-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9610838 Medline TA: Chem Commun (Camb) Country: England |
Other Details:
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Languages: eng Pagination: 665-7 Citation Subset: IM |
Affiliation:
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Department of Chemistry, UC Berkeley, Berkeley, CA, USA. |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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