Document Detail

Acid-base status of biological fluids: amount of acid, kind of acid, anion-cation difference, and buffer value.
MedLine Citation:
PMID:  6612219     Owner:  NLM     Status:  MEDLINE    
A formal concept of amount of substance of 'acid' and 'base' is proposed which is based upon the change in extent of protolytic equilibria in an arbitrary reference state for the components of the system concerned and equally consistent with the Brønsted-Lowry terminology, the older medical 'anion-cation' terminology, and the operational principle of titration. It is shown how this concept allows formulations of the 'acid-base status' of biological fluids in accordance with various types of physiological, biochemical, or clinical problems. Finally, a general expression for buffer value is presented which is valid for any acid, base, or ampholyte at any pH.
P Kildeberg
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Scandinavian journal of clinical and laboratory investigation     Volume:  43     ISSN:  0036-5513     ISO Abbreviation:  Scand. J. Clin. Lab. Invest.     Publication Date:  1983 Apr 
Date Detail:
Created Date:  1983-10-28     Completed Date:  1983-10-28     Revised Date:  2000-12-18    
Medline Journal Info:
Nlm Unique ID:  0404375     Medline TA:  Scand J Clin Lab Invest     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  103-9     Citation Subset:  IM    
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MeSH Terms
Acid-Base Equilibrium*
Hydrogen-Ion Concentration
Reg. No./Substance:
0/Anions; 0/Buffers; 0/Cations

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