Document Detail

Acid-base homeostasis with the high convective dialysis treatments.
MedLine Citation:
PMID:  12953026     Owner:  NLM     Status:  MEDLINE    
The feedback between metabolic acid production and dialytic base gain ensures a neutral acid-base balance in patients on renal replacement therapy (RRT). Despite acid not accumulating continuously, clinical studies demonstrated that normalizing pre-dialysis serum bicarbonate results in nutritional and osteodystrophy improvements. Full correction of acidosis is not an easy task in dialysis patients because it depends on both some intrinsic characteristics of patients and dialysis prescriptions. Thus, a large variation in the result is often recorded among dialysis populations and in acid-base studies. Highly convective dialysis treatments make the individualization of dialytic parameters easier than conventional dialysis. Up to now, few clinical data have been published. However, knowledge of and the quantification of the kinetic phenomena that govern the buffer transfer during a session of these high performance treatments can provide a rational approach to the optimal dialysis prescription.
Mariano Feriani
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association     Volume:  18 Suppl 7     ISSN:  0931-0509     ISO Abbreviation:  Nephrol. Dial. Transplant.     Publication Date:  2003 Aug 
Date Detail:
Created Date:  2003-09-03     Completed Date:  2004-03-17     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8706402     Medline TA:  Nephrol Dial Transplant     Country:  England    
Other Details:
Languages:  eng     Pagination:  vii26-30; discussion vii56-7     Citation Subset:  IM    
Department of Nephrology and Dialysis, Umberto 1 degrees Hospital, Mestre, Italy.
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MeSH Terms
Acid-Base Equilibrium / physiology*
Bicarbonates / blood
Renal Dialysis / methods*
Reg. No./Substance:

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