Document Detail

Acid-base disturbances in gastrointestinal disease.
MedLine Citation:
PMID:  18922984     Owner:  NLM     Status:  MEDLINE    
Disruption of normal gastrointestinal function as a result of infection, hereditary or acquired diseases, or complications of surgical procedures uncovers its important role in acid-base homeostasis. Metabolic acidosis or alkalosis may occur, depending on the nature and volume of the unregulated losses that occur. Investigation into the specific pathophysiology of gastrointestinal disorders has provided important new insights into the normal physiology of ion transport along the gut and has also provided new avenues for treatment. This review provides a brief overview of normal ion transport along the gut and then discusses the pathophysiology and treatment of the metabolic acid-base disorders that occur when normal gut function is disrupted.
F John Gennari; Wolfgang J Weise
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Publication Detail:
Type:  Journal Article; Review     Date:  2008-10-15
Journal Detail:
Title:  Clinical journal of the American Society of Nephrology : CJASN     Volume:  3     ISSN:  1555-905X     ISO Abbreviation:  -     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-11-07     Completed Date:  2009-01-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101271570     Medline TA:  Clin J Am Soc Nephrol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1861-8     Citation Subset:  IM    
Department of Medicine, University of Vermont College of Medicine, Burlington, Vermont, USA.
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MeSH Terms
Acid-Base Equilibrium*
Acidosis / etiology*,  metabolism,  physiopathology
Alkalosis / etiology*,  metabolism,  physiopathology
Digestive System / metabolism*,  physiopathology
Gastrointestinal Diseases / complications,  metabolism*,  physiopathology
Water-Electrolyte Balance*

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