Document Detail


Acid-base determinants of survival after cardiopulmonary resuscitation.
MedLine Citation:
PMID:  3931977     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The acid-base and electrolyte conditions which favor survival were examined in 105 patients during and after CPR. There was a sharp decrease in survival when arterial pH exceeded 7.55 during the initial 10 min after initiation of CPR. Measurements made one hour after successful resuscitation also demonstrated an increase in mortality when pH exceeded 7.55. Arterial blood lactate also served as a sensitive quantitative indicator of prognosis, both during and one hour after successful CPR. The adverse effects of alkalemia were largely explained by increases in whole-blood bicarbonate, plasma sodium, and plasma osmolality after administration of sodium bicarbonate.
Authors:
M H Weil; C E Ruiz; S Michaels; E C Rackow
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Critical care medicine     Volume:  13     ISSN:  0090-3493     ISO Abbreviation:  Crit. Care Med.     Publication Date:  1985 Nov 
Date Detail:
Created Date:  1985-12-02     Completed Date:  1985-12-02     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0355501     Medline TA:  Crit Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  888-92     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Acid-Base Equilibrium*
Adolescent
Adult
Aged
Bicarbonates / blood
Carbon Dioxide / blood
Female
Heart Arrest / blood*,  mortality,  therapy
Humans
Hydrogen-Ion Concentration
Lactates / blood
Male
Middle Aged
Osmolar Concentration
Potassium / blood
Prognosis
Resuscitation*
Sodium / blood
Grant Support
ID/Acronym/Agency:
GM 16462/GM/NIGMS NIH HHS; R01 HO 23015/HO/NHLBI NIH HHS
Chemical
Reg. No./Substance:
0/Bicarbonates; 0/Lactates; 124-38-9/Carbon Dioxide; 7440-09-7/Potassium; 7440-23-5/Sodium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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