| Acid base changes in arterial and central venous blood during cardiopulmonary resuscitation. | |
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MedLine Citation:
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PMID: 1326975 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Twenty-seven patients in cardiopulmonary arrest had simultaneous measurements of arterial and central venous blood gases during cardiopulmonary resuscitation (CPR) with a pneumatic chest comparison and ventilation device. Mean central venous and arterial hydrogen ion concentrations, PCO2 and calculated bicarbonate concentrations were significantly different (P less than 0.01) at all sampling times (0, 10 and 20 min). Central venous blood samples predominantly showed a respiratory acidosis in contrast to a mixed disturbance in arterial samples inclined towards a metabolic acidosis. The mean difference between central venous PCO2 (pcv CO2) and arterial PCO2 (pa CO2) ranged from 5.18 to 5.83 kPa reflecting the low blood flow in patients undergoing CPR. Measurement of arterial Po2 indicated adequate oxygenation using the pneumatic device. Arterial blood gas analysis alone does not reflect tissue acid base status. Bicarbonate administration during CPR may have adverse effects and any decision as to its use should be based on central venous blood gas estimations. |
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Authors:
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D J Steedman; C E Robertson |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Archives of emergency medicine Volume: 9 ISSN: 0264-4924 ISO Abbreviation: Arch Emerg Med Publication Date: 1992 Jun |
Date Detail:
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Created Date: 1992-11-13 Completed Date: 1992-11-13 Revised Date: 2010-09-07 |
Medline Journal Info:
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Nlm Unique ID: 8500828 Medline TA: Arch Emerg Med Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 169-76 Citation Subset: IM |
Affiliation:
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Department of Accident & Emergency Medicine, Royal Infirmary, Edinburgh. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acid-Base Imbalance
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etiology* Acidosis, Respiratory / blood Adult Aged Aged, 80 and over Arteries Bicarbonates / blood Blood Gas Analysis Carbon Dioxide / blood Cardiopulmonary Resuscitation / adverse effects* Female Heart Arrest / blood, therapy* Humans Hydrogen-Ion Concentration Male Middle Aged Prospective Studies Sodium / blood Sodium Bicarbonate Veins |
| Chemical | |
Reg. No./Substance:
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0/Bicarbonates; 124-38-9/Carbon Dioxide; 144-55-8/Sodium Bicarbonate; 7440-23-5/Sodium |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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