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Cu((i))/Amino Acid Catalyzed Coupling Reactions of Aryl Halides and Nucleophiles: Applications in Large-scale Production.
MedLine Citation:
PMID:  22273372     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Amino acids can be used as ligands to promote Ullmann-type coupling reactions. This review briefly discusses how L-proline, 4-hydroxy-L-proline and N,N-dimethylglycine can serve as the ideal ligands for copper-catalyzed coupling of aryl halides with different nucleophiles. Seven examples of applications of copper/amino acid catalyzed reactions in large-scale preparations are described.
Authors:
Dawei Ma; Yongwen Jiang
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Chimia     Volume:  65     ISSN:  0009-4293     ISO Abbreviation:  Chimia (Aarau)     Publication Date:  2011  
Date Detail:
Created Date:  2012-01-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0373152     Medline TA:  Chimia (Aarau)     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  914-8     Citation Subset:  IM    
Affiliation:
State Key Laboratory of Bioorganic and Natural Products Chemistry Shanghai Institute of Organic Chemistry Chinese Academy of Sciences 345 LingLing Road Shanghai 200032, China. madw@sioc.ac.cn.
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