Document Detail

Achieving tissue-level perfusion in the setting of acute myocardial infarction.
MedLine Citation:
PMID:  10793179     Owner:  NLM     Status:  MEDLINE    
Treatment for ST-elevation myocardial infarction (MI) has advanced rapidly in the last few years with improvements in early fibrinolytic therapy, primary percutaneous revascularization, and use of potent platelet glycoprotein IIb/IIIa inhibitors. It is now obvious that establishing epicardial patency after myocardial infarction is not synonymous with tissue-level perfusion. Techniques and therapies are now available that measure true tissue-level perfusion and that may improve tissue-level perfusion after myocardial infarction.
D Mukherjee; D J Moliterno
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The American journal of cardiology     Volume:  85     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2000 Apr 
Date Detail:
Created Date:  2000-06-06     Completed Date:  2000-06-06     Revised Date:  2013-05-24    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  39C-46C     Citation Subset:  AIM; IM    
Department of Cardiology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
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MeSH Terms
Antibodies, Monoclonal / therapeutic use
Coronary Thrombosis / physiopathology
Heart / physiopathology
Immunoglobulin Fab Fragments / therapeutic use
Myocardial Infarction / drug therapy*,  physiopathology*
Myocardial Reperfusion*
Myocardial Reperfusion Injury / physiopathology
Platelet Aggregation / physiology
Platelet Aggregation Inhibitors / therapeutic use
Platelet Glycoprotein GPIIb-IIIa Complex / therapeutic use
Regional Blood Flow
Reg. No./Substance:
0/Antibodies, Monoclonal; 0/Immunoglobulin Fab Fragments; 0/Platelet Aggregation Inhibitors; 0/Platelet Glycoprotein GPIIb-IIIa Complex; X85G7936GV/abciximab

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