Document Detail

Achieving renal denervation: catheter-based and surgical management for neural ablation in the management of hypertension.
MedLine Citation:
PMID:  23274863     Owner:  NLM     Status:  MEDLINE    
Hypertension refractory to conventional management with medication remains a significant cause of cardiovascular morbidity and mortality. Alternative strategies are warranted in this subgroup of patients. The target of these strategies centers around sympathetic neural activity, which is thought to play a key role in hypertension. We will review the historic and current approaches toward altering sympathetic neural activity, specifically discussing surgical sympathectomy, catheter-based renal denervation strategies, and baroreflex activation therapy.
Neel R Sodha; Hans J Moore; Vasilios Papademetriou; Gregory D Trachiotis
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Innovations (Philadelphia, Pa.)     Volume:  7     ISSN:  1559-0879     ISO Abbreviation:  Innovations (Phila)     Publication Date:    2012 Sep-Oct
Date Detail:
Created Date:  2012-12-31     Completed Date:  2013-06-10     Revised Date:  2013-11-07    
Medline Journal Info:
Nlm Unique ID:  101257528     Medline TA:  Innovations (Phila)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  314-22     Citation Subset:  IM    
Division of Cardiac Surgery, The Johns Hopkins Hospital, Baltimore, MD, USA.
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MeSH Terms
Catheter Ablation* / instrumentation
Equipment Design
Hypertension / surgery*
Kidney / innervation*
Sympathectomy / methods*

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