| Achieving blood pressure targets during dialysis improves control but increases intradialytic hypotension. | |
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MedLine Citation:
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PMID: 18160959 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cardiovascular disease remains the most common cause of mortality in patients with end-stage kidney disease treated by regular hemodialysis. To improve blood pressure control and reduce cardiovascular risk, the United Kingdom Renal Association standards committee introduced pre- and post-dialysis target blood pressures of less than 140/90 and 130/80 mm Hg, respectively. We audited blood pressure control and symptomatic intradialytic hypotension requiring fluid resuscitation in the Greater London area renal centers that serve 2630 patients. The study captured 7890 hemodialysis sessions during a 1-week period where only 36% of the patients achieved the pre-dialysis target and 42% the post-dialysis target, with a wide variation between centers. Different antihypertensive medication prescriptions did not affect achievement of these targets. Fifteen percent of the patients suffered symptomatic hypotension requiring fluid resuscitation associated with significantly greater interdialytic weight gains. Our study found that intradialytic hypotension was significantly greater in centers that achieved better post-dialysis blood pressure targeting. |
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Authors:
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A Davenport; C Cox; R Thuraisingham |
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Publication Detail:
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Type: Journal Article Date: 2007-12-26 |
Journal Detail:
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Title: Kidney international Volume: 73 ISSN: 1523-1755 ISO Abbreviation: Kidney Int. Publication Date: 2008 Mar |
Date Detail:
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Created Date: 2008-02-29 Completed Date: 2008-03-21 Revised Date: 2009-02-09 |
Medline Journal Info:
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Nlm Unique ID: 0323470 Medline TA: Kidney Int Country: United States |
Other Details:
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Languages: eng Pagination: 759-64 Citation Subset: IM |
Affiliation:
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UCL Center for Nephrology, Royal Free and University College Medical School, London, UK. andrew.davenport@royalfree.nhs.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Blood Pressure* Blood Pressure Determination / standards* Cardiovascular Diseases / epidemiology Female Great Britain / epidemiology Humans Hypertension / epidemiology Hypotension / epidemiology* Kidney Diseases / therapy* Male Medical Audit Middle Aged Reference Values Renal Dialysis / adverse effects* Risk |
| Comments/Corrections | |
Comment In:
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Kidney Int. 2008 Oct;74(7):963-4; author reply 964-5
[PMID:
18794820
]
Kidney Int. 2008 May;73(9):1092; author reply 1092-3 [PMID: 18414439 ] Kidney Int. 2008 Mar;73(6):667-8 [PMID: 18309346 ] Kidney Int. 2008 Dec;74(12):1624; author reply 1624-5 [PMID: 19034307 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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