Document Detail

Achalasia: new thoughts on an old disease.
MedLine Citation:
PMID:  1500657     Owner:  NLM     Status:  MEDLINE    
Achalasia is the most recognized esophageal motor disorder first described 300 years ago by Sir Thomas Willis. Although the cause of achalasia remains unknown, the disease is thought to occur as a result of degeneration of Auerbach's plexus in the intramural nervous network. A review of the literature reveals that there is reversibility of this disease in some patients after treatment, raising intriguing questions as to the pathogenesis of this disorder and underscoring the need for further study.
C M Farr
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Publication Detail:
Type:  Editorial; Review    
Journal Detail:
Title:  Journal of clinical gastroenterology     Volume:  15     ISSN:  0192-0790     ISO Abbreviation:  J. Clin. Gastroenterol.     Publication Date:  1992 Jul 
Date Detail:
Created Date:  1992-09-14     Completed Date:  1992-09-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7910017     Medline TA:  J Clin Gastroenterol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2-4     Citation Subset:  IM    
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MeSH Terms
Esophageal Achalasia / etiology*,  surgery
Esophagogastric Junction / physiopathology*,  surgery
Middle Aged
Muscle Relaxation / physiology*
Muscle, Smooth / physiopathology*
Peristalsis / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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